A new drug discovery system allows scientists to specifically target members of an important family of enzymes, called phosphatases, which were previously considered mostly “undruggable”. Scientists from the Medical Research Council (MRC) Laboratory of Molecular Biology, in Cambridge, UK, demonstrated the capabilities of the new system by identifying a molecule that could successfully target a…
Discovery of Key Component of HIV Virus Yields Drug Target
Scientists from the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge and University College London have discovered an essential feature of the HIV virus that it uses to infect cells whilst avoiding detection by the immune system. This discovery, published in Nature, presents a new drug target and the opportunity to re-evaluate existing treatments…