Neuron Death in ALS More Complex Than Previously Thought
Brown University researchers have uncovered new clues about the progression of Amyotrophic Lateral Sclerosis (ALS), a surprisingly common disease that causes the death of motor neurons that control voluntary muscles such as those involved in walking, talking, chewing or breathing. A team led by Anne Hart, a professor of neuroscience at Brown, discovered that two…
First Study on Physical Properties of Giant Cancer Cells May Inform New Treatments
Polyploidal cancer cells–cells that have more than two copies of each chromosome–are much larger than most other cancer cells, are resistant to chemotherapy and radiation treatments and are associated with disease relapse. A new study by Brown University researchers is the first to reveal key physical properties of these “giant” cancer cells. The research, published…
In Clinical Trial, Cream Reduces Squamous Cell Carcinoma Risk
New Compound Targets TB Bacterium’s Defense Against The Immune System
Part of the reason tuberculosis-causing bacteria are so good at colonizing the human body is that they have defenses against the body’s immune system. A research team led by a Brown University chemist has developed a new compound that can take down one of those defenses in Mycobacterium tuberculosis. The researchers are hopeful that the…