In recent years, a powerful suite of drugs known as kinase inhibitors have been developed to treat cancer and other diseases. Primary targets of such drugs include a family of receptor tyrosine kinases (RTKs) which protrude from cell surfaces like antennae and can activate cancer-related pathways in virtually all types of cancer when signaling molecules…
Scientists Develop New, Rapid Pipeline for Antimicrobials
With hospitals more often reaching for antibiotics of last resort to fight infections and recent Ebola and Zika outbreaks crossing borders like never before, the worldwide scientific community has been challenged with developing new antimicrobials to safeguard the population. The research arm of the U.S. Department of Defense, the Defense Advanced Research Program Agency, or…
Research Opens The Door to Improved Drugs for Type 2 Diabetes
Type 2 diabetes, a prolific killer, is on a steep ascent. According to the World Health Organization, the incidence of the condition has grown dramatically from 108 million cases in 1980 to well over 400 million today. The complex disease occurs when the body’s delicate regulation of glucose, a critical metabolite, is disrupted, creating a…