Axela Inc. introduced the dotLab Amine Reactive Sensor for stable covalent coupling of affinity reagents, such as antibodies, for use with the Axela dotLab System. The sensor directly links capture species covalently, thereby eliminating the need for offline conjugation, and reducing capture protein requirements 50-fold. The sensors are compatible with regeneration for increased throughput or rapid comparative experiments. The sensor’s lidless format makes sample recovery possible for offline mass spectrometry analysis.
Customers can order from different Amine Reactive Sensor formats: Sensor Kit, 12 sensors and a tubing set; Starter Kit, 12 sensors, tubing set, model assay test reagents, and buffers; and Activation Kit, activation reagents and buffers for amine-directed coupling.
The dotLab System employs a novel technology for performing immunoassays and the real-time study of protein interactions. The instrument automatically delivers samples and reagents to a disposable dotLab Sensor where binding events are quantitatively measured in real time. The system expands the utility of traditional immunoassays, and makes unique categories of diagnostic markers accessible for study.
Published in Drug Discovery & Development magazine: Vol. 12, No. 5, May, 2009, p.35.
Filed Under: Drug Discovery