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11 COVID-19 therapies you need to know

By Brian Buntz | December 22, 2020

9. CD24Fc recombinant fusion protein

Image courtesy of David Rini/University of Maryland.

Developers: OncoImmune/Merck (NYSE:MRK)

Description: Researchers are testing the recombinant fusion protein CD24Fc in patients with severe COVID-19 infections requiring hospitalizations.

Containing a cell surface protein known as “CD24” and another from an antibody known as “Fc,” CD24Fc was an experimental drug from a privately-held biopharmaceutical company OncoImmune. Merck negotiated a deal to acquire the company and its CD24Fc therapy in November for $425 million.

Merck also has two COVID-19 vaccines in development, although they are in an earlier stage of development than those from top rivals.

Development status: The CD24Fc protein is undergoing testing in a Phase 3 trial focusing on severely ill hospitalized COVID-19 patients.

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